Publications - Dr. Ben Black's Laboratory

Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly

Das, A., K.G. Boese, K. Tachibana, S.H. Baek, M.A. Lampson*, and B.E. Black*. 2023. Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly. Curr. Biol., 33:3759-3765. (*corresponding authors) [PMID:37582374]

The structural basis of the multi-step allosteric activation of Aurora B kinase

Segura-Peña, D., O. Hovet, H. Gogoi, J.M. Dawicki-McKenna, S.M.H. Wøien, M. Carrer, B.E. Black, M. Cascella, and N. Sekulic. 2023. The structural basis of the multi-step allosteric activation of Aurora B kinase. eLife, 12:e85328. [PMID: 36001657]

In situ structure determination of bacterial surface nanomachines using cryo-electron tomography

Lai, L., Y.-W. Cheung, M. Martinez, K. Kixmoeller, L. Palao III, S. Steimle, M.-C. Ho, B.E. Black, E.-M. Lai, and Y.-W. Chang. 2023. In situ structure determination of bacterial surface nanomachines using cryo-electron tomography. Methods Mol. Biol., 2646:211-248. [PMID:36842118]

Molecular basis of UHRF1 allosteric activation for synergistic histone modification binding by PI5P

Mandal, P., K. Eswara, Z. Yerkesh, V. Kharchenko, L. Zandarashvili, K. Szczepski, D. Bensaddek, L. Jaremko, B.E. Black, and W. Fischle. 2022. Molecular basis of UHRF1 allosteric activation for synergistic histone modification binding by PI5P. Sci. Adv., 8:eabl9461. [PMID: 36001657]

Chromosomes: a nuclear neighborhood conducive to centromere formation

Gavade, J.N., and B.E. Black*. 2022. Chromosomes: a nuclear neighborhood conducive to centromere formation. Curr. Biol., 32:R776-R778. (*corresponding author). [PMID:35882197]

Something’s gotta give at the centromeric chromatin foundation of the kinetochore

Kixmoeller, K., Allu, P.K., and B.E. Black*. 2022. Something’s gotta give at the centromeric chromatin foundation of the kinetochore. Mol. Cell., 82:1976-1978. (*corresponding author). [PMID:35659323]

Epigenetic, genetic, and maternal effects enable stable centromere inheritance

Das, A., A. Iwata-Otsubo, A. Destouni, J.M. Dawicki-McKenna, K.G. Boese, B.E. Black*, and M.A. Lampson*. 2022. Epigenetic, genetic, and maternal effects enable stable centromere inheritance. Nat. Cell Biol., 24:748-756. (*corresponding authors). [PMID:35534577]

HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications

Langelier, M.F., R. Billur, A. Sverzhinsky, B.E. Black, and J.M. Pascal. 2021. HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications. Nat. Commun. 12:6675. [PMID: 34795260]

Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub

Salinas-Luypaert, C.^†, P.K. Allu^†, G.A. Logsdon, J.M. Dawicki-McKenna, C.W. Gambogi, D. Fachinetti*, and B.E. Black*. 2021. Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A^K124ub. Cell Rep. 37:109924. (*corresponding authors; ^†contributed equally). [PMID: 34731637]

Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts

Tarasovetc, E.V., P.K. Allu, R.T. Wimbish, J.G. DeLuca, I.M. Cheeseman, B.E. Black*, and E.L. Grishchuk*. 2021. Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts. Mol. Biol. Cell, 32:1241-1255. (*corresponding authors). [PMID: 33956511]

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