Archive for the ‘News’ Category

April 2019

Peder and Yekaterina’s methods article on protein acetylation is published in Methods in Molecular Biology, and a collaboration with the Blobel lab (CHOP) on the role of histone acetylation during mitotic transcription is published in Cell Reports.

Khadija is awarded an NSF Graduate Fellowship, and Hee Jong is named Honorable Mention for the NSF Graduate Fellowship, congratulations to both!

Abby wins the Garcia Lab 9th Floor Ballers NCAA Bracket Tournament Challenge, correctly being the only one to select UVa as the Champion. Ben and Peder finished a respectable 2nd and 3rd. “Auburn Joe” is born, and Amber, please stick to surface proteins

The Garcia lab welcomes visiting graduate student Hilde von Gruning (University of Pretoria) to the group for a short research collaboration stay.

March 2019

Collaborations with the Morrisey lab (UPenn) to study transcriptional factors that regulate lung epithelial homeostasis and with the Allis lab (Rockefeller University) to determine the cellular target of menin inhibition in glioma are published in Gene & Development and PNAS, respectively.

John’s work on the epigenetic mechanisms in MPNST cancers is published in Cancer Research, congrats!

Yekaterina gave a talk, and our former summer HS student Bella presented a poster at the Pittcon Conference in Philadelphia, PA.

Collaborations with the Maze lab (Mt. Sinai) on a new histone modification sertonylation, and with the Jabado lab (McGill University) to further understand how the H3K27M mutation affects H3K27 methylation spreading are published in Nature and Nature Communications, respectively. Additionally,  Bhanu’s work describing signaling cross-talk with a trans-histone code during myogenesis is published in the Journal of Biological Chemistry, congrats.

The Garcia Lab is the featured lab of the month on the Epigenetics Institute website, check out the video here, and the Garcia Lab blog post here.

The Garcia Lab will have 4 talks (Josue, Zuo-Fei, Amber and Mariel C), and 12 posters at the ASMS Conference later this year, watch out Atlanta!

The Garcia Lab returns from the US HUPO Conference in Rockville, MD. Mariel C., Peder and Richard gave short talks; Khadija, Zuo-Fei, Kasia and Congcong gave lightning talks; Yekaterina gave a Tips & Tricks talk and Ben gave an invited talk. We also had poster presentations from Josue, Yekaterina, Jen, Khadija, Joe, Kasia, Abby, Bhanu, Zuo-Fei, Congcong and Super M. Last but not least, Yekaterina also won first place in the graduate student poster competition!

Richard’s collaboration with the Bonasio and Davidovich labs to map RNA-protein binding sites on the EZH2 complex that influence its activity is published in Nat Struct Mol Biol.

Mariel C. has been selected to attend the Lindau Nobel Laureate meeting in Germany, congrats!

Sam successfully defends his PhD thesis, congratulations Dr. Wein!

The Garcia Lab says goodbye to Simone, who is off to start his independent faculty position at the Einstein College of Medicine, you’ll be missed, best of luck!

February 2019

Abby has been selected to receive an Undergraduate Student travel award from the American Society for Mass Spectrometry (ASMS) to attend the annual ASMS conference in June, congratulations!

Former graduate student Kelly Karch has received a President’s Postdoctoral Scholars Fellowship from the Ohio State University to join Vicki Wysocki’s lab for her postdoctoral studies, congrats!

Mariel C. has been awarded a Graduate Student travel award from the American Society for Mass Spectrometry (ASMS) to attend the annual ASMS conference in June, congrats!

Amber has been selected to receive an AACR-Margaret Foti Scholar-in-Training award from the American Association for Cancer Research, congrats!

A collaborative study with the Berger lab (UPenn) on the role of p300 in senescence is published in Molecular Cell.

Congcong’s multi-omics study to interrogate signaling pathway crosstalk and epigenetic mechanisms during the epithelial to mesenchymal transition in cancer is published in Epigenetics and Chromatin.

Peder has been awarded a travel award to attend the US-HUPO conference next month.

Simone publishes a methods article on understanding the role of acetyl-CoA metabolism and histone modifications.

Peder has received a Chrohn’s and Colitis Foundation Postdoctoral Fellowship, congratulations!

Josue is awarded an American Society for Mass Spectrometry Postdoctoral Career Development Award, congrats!

The Garcia Lab says goodbye to Anumita, who will be starting her new position at Merck, good luck!

January 2019

The Garcia Lab welcomes our new BMB rotation students Kollin Schultz and Michael Gilbert to the group.

Collaborative studies with the Zaret lab (UPenn) on the role of heterochromatin during lineage commitment, and with the Wellen lab (UPenn) on the role of acetyl-CoA metabolism in pancreatic cancer are published in Science, and Cancer Discovery, respectively.

December 2018

Hee Jong has has been awarded an NIH Chemistry-Biology Interface graduate training fellowship, well done!

A collaborative manuscript with the Pierce lab (UPenn) to understand epigenetic mechanisms behind transgenerational cocaine addiction and behavioral consequences is published in the European Journal of Neuroscience.

The Garcia Lab says goodbye to Ranran, who will be starting a new position at MD Anderson in Houston, best of luck!

The Garcia Lab had the annual Holiday Party with food, games and a gift exchange. Bhanu won the best “ugliest” sweater contest, although there were several top contenders.

Sam’s preprint of his nucleics acids search enginine computaitonal platform is picking up by the Proteomics News BlogSpot.

The Garcia Lab participates in the Chemistry-Biology Interface Symposium. Simone gave a talk, and several members gave posters including Joe who won second place for his poster presentation.

Dylan and John’s review on cancer epigenetics is published in Expert Review in Proteomics.

Stephanie is awarded a Michael S. Brown Penn-GSK Postdoctoral Fellowship, congrats!

November 2018

Ben returns from BGS graduate student recruiting at the ABRCMS conference in Indianapolis. Former Garcia Lab summer student Nia Harmon gave an excellent talk.

The Garcia Lab returns from the Department/BMB graduate program retreat at the Poconos Mountains. We had several poster presentations (Josue, Yekaterina, Sam, Kevin, Richard, Mariel C, Mariel M, Dylan and Laura). Mariel C won second place in the poster competition and Ben defended his “Student Outreach” award title.

Anumita, Geoff and Jen present at the annual Biomedical Postdoctoral Research Symposium on campus, nice work!

Collaborations with the Kashina lab (UPenn) on the human arginylome, and with the Berger lab on histone modifications changes in clinically abnormal sperm are published in Scientific Reports, and the Journal of Assisted Reproduction and Genetics, respectively.

The Garcia Lab says goodbye to Mariana Lopes, our visiting graduate student who will be going back to Brazil to finish her PhD studies.

Ben is named the John McCrea Dickson M.D. Presidential Professor.

October 2018

The Garcia Lab welcomes our two new Chemistry rotation students Alice Wei and Tongheng Chen to the lab.

The Garcia Lab welcomes our new postdoc Stephanie Miller Lehman to Philly.

Ben is interviewed by The Analytical Scientist, read here.

Kelly’s manuscript describing  Top and Middle Down Hydrogen-Deuterium exchange MS approaches for probing nucleosomal conformation is published in Structure.

Ben participates in a Panel Discussion on the past, present and future of quantitative proteomics for the ProteomicsNOW MS Virtual Event ( sponsored by Thermo Fisher Scientific and Wiley Publishing.

Our collaboration with the Greenberg Lab describing the effect of phosphorylation on TIP60 during DNA damage is published in Molecular and Cellular Biology.

The Garcia Lab returns from a great experience at the HUPO 2018 conference in Orlando, FL. We had multiple poster presentations from the lab (Kasia, Jen, Josue, John, Dylan, Kevin, Mariel M, Amber, Joe, Yekaterina, Bhanu, Peder and Geoff). Amber was also chosen as one of 8 Finalists for the PhD Poster Competition, where she gave a 3 min short talk on her work. Later she was selected as one of the 3 winners of the competition!  Laura, Mariel and Ben gave talks, and Yekaterina won a travel award. Overall, it was a fantastic conference and fun time.

September 2018

Collaboration with the Locasale lab (Duke) to understand acetate production from glucose is published in Cell.

Congratulations to Simone, who has accepted an offer to start his own lab at the Albert Einstein College of Medicine!

Our collaborative work with the Strome lab (UC Santa Cruz) to understand epigenetic memory and transmission of histone H3K36 methylation is published in Genetics.

Mariel M has been awarded an NIH Diversity Supplement grant award from the National Cancer Institute, congrats!

The Garcia lab welcomes Janice Reynaga and Neha Srikumar (both BMB graduate students) to the lab for the fall rotation.

August 2018

Yekaterina has been selected receive a travel award to present her work at the 2018 HUPO World Congress next month, congrats.

Ben Garcia is named to the editorial board of Molecular Omics, read here.

The Garcia Lab has a fun time at the Department of Biochemistry and Biophysics picnic. Kevin, Laura, Simone, Bella, Alina and Ben even helped the department team (“RNAces”) beat the Physiology department in the big softball game 4-3 (Bella even knocked in the winning run!).

Amber has been named a finalist for the PhD Poster Competition at next month’s World HUPO Congress. She will give a short presentation and compete against 7 other finalists, read here. Good luck!

The Garcia Lab says goodbye to Dr. Kelly Karch, who will travel the world before moving onto a postdoc position.

The Garcia Lab also says goodbye to our summer undergrad and HS researchers: Emily, Maura, Bella, Ayushi and Nia. Thanks for all the hard work!

Collaborative papers with Gerd Blobel (CHOP) and Jenny Brodbelt (UT Austin) are published in Science and the Journal of Proteome Research, respectively.

July 2018

The Garcia Lab has their annual Summer Lab Party. It was a really good time, lots of food (histone salad and nucleosome cake) and sports activities. Congratulations to Kevin and Simone (“Kev-mone”) for overcoming their differences and coming together to win the Wii Boxing Tournament!

Mariel C presented a poster on her work at the first annual Office of Research and Diversity Training Research Symposium here on campus.

Amber’s NIH F31 NRSA Predoctoral Fellowship is funded by the National Cancer Institute, congratulations!

Excited to announce that John Wojcik has officially started as an Assistant Professor in the Department of Pathology and Laboratory Medicine here at the University of Pennsylvania School of Medicine. Congratulations John, and looking forward to big things in the future from your new lab!

Ben and Donita Brady (Cancer Biology) are interviewed to discuss the Presidential Professorship and diversity in science by UPenn’s Office of Inclusion and Diversity (OID). This interview was included in the OID Annual Report (Page 7) which can be read here.

Hendrik Weisser from STORM Therapeutics visits the Garcia Lab and gives a seminar on the latest in RNA modifications analysis for therapeutic use.

Khadija has been awarded an NIH Pharmacology T32 graduate training fellowship, congrats!

Ben has been featured on the American Chemical Society (ACS) Scholars Alumni Profile Series, read here.