Select Publications

Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome structural transition

Guo, L.Y., P.K. Allu, L. Zandarashvili, K.L. McKinley, N. Sekulic, J.M. Dawicki-McKenna, D. Fachinetti, G.A. Logsdon, R.M. Jamiolkowski, D.W. Cleveland, I.M. Cheeseman, and B.E. Black*. 2017. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome structural transition. Nat. Commun., 8:15775. (*corresponding author) PMID: 28598437

Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

Nechemia-Arbely, Y., D. Fachinetti, K.H. Miga, N. Sekulic, G.V. Soni, D.H. Kim, A.K. Wong, A.Y. Lee, K. Nguyen, C. Dekker, B. Ren, B.E. Black, and D.W. Cleveland. 2017. Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points. J. Cell Biol., 216:607-621. PMID: 28235947

CENP-A post-translational modifications on Ser68 and Lys124 are dispensable for establishment, maintenance, and long-term function of human centromeres

Fachinetti, D., G.A. Logsdon, A. Abdullah, E.B. Selzer, D.W. Cleveland*, and B.E. Black*. 2017. CENP-A post-translational modifications on Ser68 and Lys124 are dispensable for establishment, maintenance, and long-term function of human centromeres. Dev. Cell, 40:104-113. (*corresponding authors; contributed equally) PMID: 28073008

A dual inhibitory mechanism sufficient to maintain cell cycle restricted CENP-A assembly

Stankovic, A., L.Y. Guo, J.F. Mata, D.L. Bodor, X.-J. Cao, A.O. Bailey, J. Shabanowitz, D.F. Hunt, B.A. Garcia, B.E. Black*, and L.E.T. Jansen*. 2017. A dual inhibitory mechanism sufficient to maintain cell cycle restricted CENP-A assembly. Mol. Cell, 65:231-246. (*corresponding authors) PMID: 28017591

Preparation of recombinant centromeric nucleosomes and formation of complexes with non-histone centromere proteins

Sekulic, N., and B.E. Black*. 2016. Preparation of recombinant centromeric nucleosomes and formation of complexes with non-histone centromere proteins. Methods Enzymol., 573:67-96. (*corresponding author) PMID: 27372749

A core viral protein binds host nucleosomes to sequester immune danger signals

Avgousti, D.C., C. Herrmann, K. Kulej, N.J. Pancholi, N. Sekulic, J. Petrescu, R.C. Molden, D. Blumenthal, A.J. Paris, E.D. Reyes, P. Ostapchuk, P. Hearing, S.H. Seeholzer, G.S. Worthen, B.E. Black, B.A. Garcia, and M.D. Weitzman. 2016. A core viral protein binds host nucleosomes to sequester immune danger signals. Nature, 535:173-177. PMID: 27362237

Long-term retention of CENP-A nucleosomes in mammalian oocytes underpins transgenerational inheritance of centromere identity

Smoak, E.M., P. Stein, R.M. Schultz, M.A. Lampson*, and B.E. Black*. 2016. Long-term retention of CENP-A nucleosomes in mammalian oocytes underpins transgenerational inheritance of centromere identity. Curr. Biol., 26:1110-1116. (*corresponding authors) PMID: 27040782

CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres

Falk, S.J., J. Lee, N. Sekulic, M.A. Sennett, T.-H. Lee*, and B.E. Black*. 2016. CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres. Nat. Struct. Mol. Biol., 23:204-208. (*corresponding authors; contributed equally) PMID: 26878239

Bistability of a coupled Aurora B kinase-phosphatase system in cell division

Zaytsev, A.V., D. Sagura-Peña, M. Godzi, A. Calderon, E.R. Ballister, R. Stamatov, A.M. Mayo, L. Peterson, B.E. Black, F.L. Ataullakhanov*, M.A. Lampson*, E.L. Grishchuk*. 2016. Bistability of a coupled Aurora B kinase-phosphatase system in cell division. Elife, 5:e10644. (*corresponding authors; contributed equally) PMID: 26765564

Identification of the posttranslational modifications present in centromeric chromatin

Bailey, A.O., T. Panchenko, J. Shabanowitz, S.M. Lehman, D.L. Bai, D.F. Hunt, B.E. Black*, and D.R. Foltz*. 2016. Identification of the posttranslational modifications present in centromeric chromatin. Mol. Cell. Proteomics, 15:918-931. (*corresponding authors; contributed equally) PMID: 26685127