Giacomo Cavalli, Ph.D. – Distinguished Seminar Series | Epigenetics Seminar

Giacomo Cavalli, Ph.D.
Chromatin and Cell Biology lab, Institute of Human Genetics – CNRS

Lab web page
Twitter @giacomo_cavalli:

Giacomo Cavalli has studied Biology at the University of Parma. In 1991, he moved to Zürich at the University of Science and Technology (ETH) and did his PhD working on chromatin structure and function in yeast. From 1995 to 1998, he was postdoc in the laboratory of Prof. Renato Paro at the University of Heidelberg. In 1999, he moved to IGH to set up a junior lab and stayed at IGH ever since. Giacomo Cavalli made seminal contributions in the field of epigenetics. Using the fruit fly Drosophila melanogaster, he discovered that epigenetic inheritance of new phenotypes can occur independently on changes of the DNA sequence. His lab also discovered that the three-dimensional organization of chromosome in the cell nucleus is an epigenetically heritable trait that plays an important gene regulatory role. The Cavalli lab identified 3D structural chromosomal domains dubbed Topologically Associating Domains or TADs. Finally, the Cavalli lab has shown that PcG proteins have tumor suppression activity in flies. Giacomo Cavalli has received numerous awards and distinctions, including an EMBO membership, the CNRS silver medal, the Allianz Foundation price, the Grand Prix of the Fondation pour la Recherche Médicale and two advanced ERC grants. He organized major international conferences and is appointed as members of several distinguished scientific boards.

Giacomo Cavalli Seminar_15Mar2021

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