Highly Mutated Protein in Skin Cancer Plays Central Role in Skin Cell Renewal
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“Icebreaker” Protein Opens Genome for T cell Development, Penn Researchers Find
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New genomic analyses indicate that pioneer transcription factors can sample a diverse repertoire of common binding sites among different cell types and become enriched where they cooperate with other factors specific to each cell. Pioneer-factor binding is mechanistically separate from, and is necessary for, subsequent phenomena of chromatin opening and epigenetic memory in vivo.
Penn Study on Super-silenced DNA Hints at New Ways to Reprogram Cells
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Penn Study Shows How Female Immune Cells Keep Their Second X Chromosome Shut Off
Research led by Rajan Jain and Jonathan Epstein of the Perelman School of Medicine suggests that the three-dimensional organization of DNA in the nucleus determines a cell’s ultimate destiny.
PIK professors Michael Platt and Shelley Berger are embarking on a joint research project focused on how stress affects the brain and behavior.
They discussed their burgeoning collaboration with Knowledge@Warton.
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Cell Stress Response Sheds Light on Treating Inflammation-related Cancer, Aging
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How Brain Develops Before Birth is Tightly Controlled by RNA Modification
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