Department of Bioengineering
School of Engineering and Applied Sciences
University of Pennsylvania
210 South 33rd Street
Lab: 240 Skirkanich Hall
Office: 304 Hayden Hall
Philadelphia, PA 19104
Office: 215.898.4121
jcremins@seas.upenn.edu
Epigenomics and Systems Neurobiology Lab: The Cremins Lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of neural cell function. We employ systems level experimental and computational approaches to (1) create high-resolution 3-D genome architecture maps and (2) integrate 3-D architecture maps with genome-wide maps of epigenetic modifications and gene expression. Current work is focused on understanding the role for higher-order chromatin organization during differentiation of embryonic stem cells into neurons, during reprogramming of neurons into induced pluripotent stem cells and in models of neurodegenerative disease.
FIRST NAME: | LAST NAME: | TITLE: | EMAIL: |
---|---|---|---|
Jennifer | Phillips-Cremins | PI | jcremins@seas.upenn.edu |
Jonathan | Beagan | PhD Graduate Student | jbeagan@seas.upenn.edu |
Michael | Guo | Resident (PGY-2), Department of Neurology | mduong@sas.upenn.edu |
Thomas | Gilgenast | PhD Graduate Student | tgg@seas.upenn.edu |
Wanfeng | Gong | Research Specialist | wanfeng@seas.upenn.edu |
Harshini | Chandrashekar | Computational Scientist I | hchand@seas.upenn.edu |
Miriam | Minsk | Undergraduate Student | mminsk@seas.upenn.edu |
Daniel | Emerson | Computational Scientist I | demerson368@gmail.com |
Lindsey | Fernandez | PhD Graduate Student | lifer@seas.upenn.edu |
Kelly | Feng | Undergraduate Student | kfeng99@sas.upenn.edu |
Ravi | Boya | Postdoctoral Associate | bravi.uohyd@gmail.com |
Heesun | Choi | Postdoctoral Associate | hschoi@seas.upenn.edu |
Kate | Titus | Graduate Student | katetitus1@gmail.com |
Linda | Zhou | MD/PhD graduate student | Linda.Zhou@uphs.upenn.edu |
Chuanbin | Su | Postdoctoral Associate | chuanbin@seas.upenn.edu |
Lindsey | Fernandez | PhD Graduate Student | lifer@seas.upenn.edu |
Alexandria | Nikish | PhD Graduate Student | anikish@seas.upenn.edu |
Simandi | Zoltan | Postdoctoral Associate | simandizoltan@gmail.com |
Chunmin | Ge | Research Specialist | cmge@seas.upenn.edu |
Copley | Katie | Rotation student | kcopley@pennmedicine.upenn.edu |
Franklin | Brian | Rotation student | brian.franklin1@pennmedicine.upenn.edu |