Jennifer E. Phillips-Cremins, Ph.D.
Contact Information
Department of Bioengineering
School of Engineering and Applied Sciences
University of Pennsylvania
210 South 33rd Street
Lab: 515 Skirkanich Hall
Office: 304 Hayden Hall
Philadelphia, PA 19104
Office: 215.898.4121
jcremins@seas.upenn.edu
Publication Links
Research Interest
Epigenomics and Systems Neurobiology Lab: The Cremins Lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of neural cell function. We employ systems level experimental and computational approaches to (1) create high-resolution 3-D genome architecture maps and (2) integrate 3-D architecture maps with genome-wide maps of epigenetic modifications and gene expression. Current work is focused on understanding the role for higher-order chromatin organization during differentiation of embryonic stem cells into neurons, during reprogramming of neurons into induced pluripotent stem cells and in models of neurodegenerative disease.