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Archive for 2016

A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly

A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly. Stankovic A, Guo LY, Mata JF, Bodor DL, Cao XJ, Bailey AO, Shabanowitz J, Hunt DF, Garcia BA, Black BE, Jansen LE.  Mol Cell. 2017 Jan 19;65(2):231-246.

Why proteomics is not the new genomics and the future of mass spectrometry in cell biology

Why proteomics is not the new genomics and the future of mass spectrometry in cell biology. Sidoli S, Kulej K, Garcia BA. J Cell Biol. 2017 Jan 2;216(1):21-24.

Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine

Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine. Liu MY, Torabifard H, Crawford DJ, DeNizio JE, Cao XJ, Garcia BA, Cisneros GA, Kohli RM.  Nat Chem Biol. 2017 Feb;13(2):181-187.

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, La Rocca G, Santi M, Lewis PW, Hawkins C, Melnick A, David Allis C, Thompson CB, Chinnaiyan AM, Judkins AR, Venneti S. Sci Transl Med. 2016 Nov 23;8(366):366ra161.

Characterization of Individual Histone Posttranslational Modifications and Their Combinatorial Patterns by Mass Spectrometry-Based Proteomics Strategies

Characterization of Individual Histone Posttranslational Modifications and Their Combinatorial Patterns by Mass Spectrometry-Based Proteomics Strategies. Sidoli S, Garcia BA. Methods Mol Biol. 2017;1528:121-148.

Global Proteomics Analysis of Protein Lysine Methylation

Global Proteomics Analysis of Protein Lysine Methylation. Cao XJ, Garcia BA. Curr Protoc Protein Sci. 2016 Nov 1;86:24.8.1-24.8.19.

High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells

High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells. He C, Sidoli S, Warneford-Thomson R, Tatomer DC, Wilusz JE, Garcia BA, Bonasio R. Mol Cell. 2016 Oct 20;64(2):416-430.

Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription

Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. Josefowicz SZ, Shimada M, Armache A, Li CH, Miller RM, Lin S, Yang A, Dill BD, Molina H, Park HS, Garcia BA, Taunton J, Roeder RG, Allis CD. Mol Cell. 2016 Oct 20;64(2):347-361.

Identification and Quantification of Histone PTMs Using High-Resolution Mass Spectrometry

Identification and Quantification of Histone PTMs Using High-Resolution Mass Spectrometry. Karch KR, Sidoli S, Garcia BA. Methods Enzymol. 2016;574:3-29.

A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of GABAA Receptor Subunit Binding Selectivity in Synaptosomes

A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of GABAA Receptor Subunit Binding Selectivity in Synaptosomes. Woll KA, Murlidaran S, Pinch BJ, Hénin J, Wang X, Salari R, Covarrubias M, Dailey WP, Brannigan G, Garcia BA, Eckenhoff RG.  J Biol Chem. 2016 Sep 23;291(39):20473-86.