Archive for the ‘News’ Category

July 2016

Collaborative papers with the Adams Lab (University of Glasgow) and Eckenhoff Lab (Penn) are published in Genome Biology and the Journal of Biological Chemistry, respectively.

The Garcia Lab says goodbye to Visiting Professor Xiaolu Zhao who will be returning to Wuhan University.

Ben gives a talk and receives the Protein Science Young Investigator Award at the 30th Protein Society Symposium in Baltimore, MD.

The Garcia Lab comes backs from another great GRAAM (Garcia, Roeder, Allis, Armstrong, Muir) super chromatin group meeting at Rockefeller University. Johayra represented the lab by presenting her work on fatty-acyl histone modifications.

Kasia’s collaborative work with the Weitzman Lab (CHOP) on the role of protein VII in modulating chromatin structure during adenovirus infection is published in Nature, congrats!

June 2016

Two collaborative grants have been awarded funding. Our internal Penn ITMAT grant with Doug Wallace (CHOP) to study epigenetic effects of mitochondrial dysfunction, and an NIH R21 grant with Chris Pierce (Penn) to investigate cocaine addiction and the epigenome. Congrats all around!

Peder has been awarded a postdoctoral fellowship on the  NCI-funded T32 Immunobiology of normal and neoplastic lymphocytes training grant. Congrats!

The Garcia Lab comes back from a fantastic ASMS Conference in San Antonio. We had poster presentations from Mariel, Johayra, Simone, Bhanu, Sam, Zuo-Fei, XJ, Kasia and Amber. Kelly and Ben also gave talks in the protein PTMs and stable isotope labeling sessions.

Simone’s work on quantification of phosphopeptide isomers using data independent acquisition MS is published in Molecular BioSystems, while Xiaoshi’s collaborative work with the Berger and Reinberg lab’s is published in Epigenetics and Chromatin, and Nature, respectively.

Dylan is awarded a Structural Biology and Molecular Biophysics training program graduate fellowship. Congrats!

The Garcia Lab welcomes incoming BMB graduate student Yekaterina Kori to the group for a summer rotation.

Ben speaks at Wallingford Elementary School about chemicals and how they affect our lives.

Amber has passed her 2nd year prelim exam, congratulations!

Mariel is awarded an NIH Research Supplement to promote diversity in health-related research to support her PhD studies, congrats!

Graduate student Laura Agosto (BMB) joins the lab (joint student with Kristen Lynch). Welcome to the group!

Amber has been awarded an Alex’s Lemonade Stand Foundation (ALSF) graduate fellowship in pediatric cancer research, congrats!

May 2016

Shu’s research on asymmetric phosphorylation of old histones is published in the Journal of Biological Chemistry, while Simone’s manuscript describing a newer multiplexing data independent acquisition method is accepted by the Proteomics journal.

Ben speaks to students at Strathhaven Middle School about the importance of scientific research for human health during the Dimensions in Living career day.

The Garcia Lab’s first major motion picture is finished starring Kelly, Bhanu and Simone. See our Journal of Visualized Experiments (JoVE) publication and video demonstrating our Bottom Up MS protocol for histone PTM analysis.

Mariel and Kevin have passed their 2nd year prelim exams, congratulations!

Our collaborative study to understand the effects of histone H3K36 mutations in sarcomas is published in Science.

The Garcia Lab says goodbye to Tara who has finished her undergraduate studies at Penn and will be off to graduate school at Columbia University, congrats!

Collaborative studies with the Witze lab (Penn) and Dou lab (Michigan) are published in Molecular Cell. These studies feature experiments performed by Garcia Lab members Bhanu, Xing-Jun and Qi.

Mariel has been awarded a Delaware Valley Mass Spectrometry Discussion Group travel award to present her poster at the upcoming 64th American Society for Mass Spectrometry Conference. Congratulations!

Edwin has been awarded an NIH NRSA F31 Graduate Fellowship, congrats!

Simone has been awarded a New Jersey Section American Chemical Society Mass Spectrometry Discussion Group travel award to present his poster at the 64th American Society for Mass Spectrometry Conference.  Congrats!

April 2016

Xiaoshi’s paper on GlcNAc dynamics is accepted by Molecular and Cellular Proteomics.

The Garcia lab says goodbye to Dr. Xiaoshi Wang who will be starting the next phase of her career at Novavax, congratulations!

The Garcia Lab comes backs from a productive GRAAM (Garcia, Roeder, Allis, Armstrong, Muir) super chromatin group meeting at Princeton University. Yumiao represented the lab by presenting her work on cellular signaling into chromatin.

Dr. Ranran Wu joins the Garcia Lab as a Postdoctoral Scientist, welcome!

March 2016

The new Penn SOM Quantitative Proteomics Core is officially open. Dr. Xing-Jun Cao will oversee the core as the Technical Director, and Dr. Rong Meng has started as a Research Specialist.

Anna’s paper combining click chemistry and mass spectrometry to investigate newly synthesized histones is now published in ACS Chemical Biology.

The Garcia Lab attends the US HUPO Conference in Boston. We had featured talks by Simone and Kelly, and “lightning” talks by Sam and Kasia. Zuo-Fei, Sam, Kasia and Bhanu also presented posters, and Ben led an evening workshop.  All in all, it was a fantastic combination of great science and a good time.

John has been awarded a K12 Paul Calabresi Career Development Award for Clinical Oncology, congratulations!

Graduate student Dylan Marchione (PGG) joins the Garcia Lab, welcome!

The special issue of Molecular and Cellular Proteomics (MCP) focused on Chromatin Biology and Epigenetics where Ben was a special guest editor is now published! Check out the special cover image artwork commissioned for this issue which had significant input from Ben and Simone.

Yumiao’s chemical proteomics approach to map signaling pathway interactions with chromatin is published in Molecular and Cellular Proteomics.

Collaborative studies to understand global lysine methylation and intact histone proteoforms are published in Molecular and Cellular Proteomics. These publications feature research by Kelly, Mariel, Simone and Xing-Jun, congrats.

February 2016

Team Oncohistone (Congcong, Johayra, Bhanu, Simone and Zuo-Fei) had a productive kickoff meeting with the other NIH P01 grant team labs (Dave Allis, Tom Muir, Peter Lewis and Nada Jabado labs) up at Rockefeller University.  Progress on understanding the epigenetic aspects of childhood brain and other cancers will be updated at

The Garcia lab presents in the Biochemistry and Molecular Biophysics Department Friday research discussion. Marial and Yumiao presented their latest results from their studies, nice job!

Ben Garcia has won the 2016 Young Investigator Award from The Protein Society. Read the Penn press release here.

New Postdoctoral researcher Peder Lund  joins the Garcia lab.

Michelle’s work on the role of histone H4 acetylation and their reader Brd4 in embryonic stems cells is published in BMC Genomics.

Visiting Professor Dr. Xiaolu Zhao arrives in the lab, welcome!

Bhanu’s research on identifying epigenetic signatures during stem cell renewal and differentiation is published in Proteomics.

January 2016

The Garcia lab welcomes rotation students Keith Campagno and Ziyang Xu to the lab.

We welcome our new postdoc Dr. Yanping Lin to the lab.

December 2015

The Garcia Lab had their annual Holiday Party. There was lots of good food, a gift exchange, Kelly won the Wii Just Dance tournament, and we also said goodbye to Shu who will be leaving for her new position at Dartmouth University, congrats!

Ben Garcia attends the Enabling Technologies Proteomics (ETP) Symposium held in Lake Louise, Canada, where he gives an invited talk and also receives the ETP Ken Standing Award.

The Garcia lab says goodbye to Dr. Shu Lin who has accepted a Scientist position at Dartmouth University, Congrats!

November 2015

Genome Web publishes a story on our methodology to link cellular signaling to chromatin mediated gene expression.

The Garcia Lab attends the Biochemistry and Biophysics departmental retreat at the Skytop Lodge in the Pocono Mountains. Simone gave a nice talk, and Kelly won the First Place Kate Ferguson Award in Biochemistry for her poster presentation, congrats!

Qi Guo joins the lab as a Technician, welcome!

Ben Garcia gives an invited talk at the Canadian Cancer Research Conference in Montreal, Canada.

September 2015

Ben gives an invited talk at the World HUPO Congress in Vancouver, BC, Canada.

Visiting graduate student Catarina Charneira (Instituto Superior Técnico, Portugal) joins the lab.

Undergraduate Tara Lorimer joins the lab for her senior thesis work, welcome!

The Garcia lab welcomes rotation students Laura Agosto and Hannah Richter to the lab.