Publications

Single Cell Proteomics to Study Embryonic Asymmetry in Xenopus laevis Embryos

Single Cell Proteomics to Study Embryonic Asymmetry in Xenopus laevis Embryos. Saha-Shah A, Esmaeili M, Sidoli S, Hwang H, Yang J, Klein PS, Garcia BA. Anal Chem. 2019 Jun 13. doi: 10.1021/acs.analchem.9b00327. [Epub ahead of print]

Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss

Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss. Marchione DM, Lisby A, Viaene AN, Santi M, Nasrallah M, Wang LP, Williams EA, Larque AB, Chebib I, Garcia BA, Wojcik JB. Mod Pathol. 2019 Jun 7. doi: 10.1038/s41379-019-0287-8. [Epub ahead of print]

Novel functions of the ubiquitin-independent proteasome system in regulating Xenopus germline development

Novel functions of the ubiquitin-independent proteasome system in regulating Xenopus germline development. Hwang H, Jin Z, Krishnamurthy VV, Saha A, Klein PS, Garcia B, Mei W, King ML, Zhang K, Yang J. Development. 2019 Apr 23;146(8).

The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells

The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, Garcia BA, Hardison RC, Shi J, Blobel GA. Blood Adv. 2019 May 28;3(10):1586-1597

One minute analysis of 200 histone post-translational modifications by direct injection mass spectrometry

One minute analysis of 200 histone post-translational modifications by direct injection mass spectrometry. Sidoli S, Kori Y, Lopes M, Yuan ZF, Kim HJ, Kulej K, Janssen KA, Agosto LM, Cunha JPC, Andrews AJ, Garcia BA. Genome Res. 2019 Jun;29(6):978-987.

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. Jain SU, Do TJ, Lund PJ, Rashoff AQ, Diehl KL, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir TW, Garcia BA, Jabado N, Lewis PW. Nat Commun. 2019 May 13;10(1):2146.

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, Weil AG, Ursini-Siegel J, De Carvalho DD, Dirks PB, Lewis PW, Salomoni P, Lupien M, Arrowsmith C, Lasko PF, Garcia BA, Kleinman CL, Jabado N, Mack SC. Cancer Cell. 2019 May 13;35(5):782-797.

Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond

Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond. Lund PJ, Kori Y, Zhao X, Sidoli S, Yuan ZF, Garcia BA. Methods Mol Biol. 2019;1977:43-70.

Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription

Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA. Cell Rep. 2019 Apr 9;27(2):400-415.

The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration

The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration. Swarr DT, Herriges M, Li S, Morley M, Fernandes S, Sridharan A, Zhou S, Garcia BA, Stewart K, Morrisey EE. Genes Dev. 2019 Jun 1;33(11-12):656-668.