Publications
Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes. Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, Aanchal Mongia, Maria L. Golson, Yue J. Wang, Ashleigh Morgan, Chengyang Liu, Jonathan Schug, Jinping Liu, Minghui Wu, Daniel Traum, Ayano Kondo, Catherine L. May, Naomi…
Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry. Minghui Wu, Michelle Y Y Lee, Varun Bahl, Daniel Traum, Jonathan Schug, Irina Kusmartseva, Mark A Atkinson, Guanjie Fan, HPAP Consortium; Klaus H Kaestner.
Temporal manipulation of Cdkl5 reveals essential postdevelopmental functions and reversible CDKL5 deficiency disorder–related deficits. Barbara Terzic, M. Felicia Davatolhagh, Yugong Ho, Sheng Tang, Yu-Ting Liu, Zijie Xia, Yue Cui, Marc V. Fuccillo, and Zhaolan Zhou.
Highly multiplexed image analysis of intestinal tissue sections in patients with inflammatory bowel disease. Ayano Kondo, Siyuan Ma, Michelle Y.Y. Lee, Vivian Ortiz, Daniel Traum, Jonathan Schug, Benjamin Wilkins, Natalie A. Terry, Hongzhe Lee, Klaus…
Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing. Tingfang Chen, Alex M. Rohacek, Matthew Caporizzo, Amir Nankali, Jeroen J. Smits, Jaap Oostrik, Cornelis P. Lanting, Erdi Kücük, Christian Gilissen, Jiddeke M. van de…
Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution. Daniel Aldea, Yuji Atsuta, Blerina Kokalari, Stephen F. Schaffner, Rexxi D. Prasasya, Adam Aharoni, Heather L. Dingwall, Bailey Warder, and Yana G. Kamberov.
Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia. Osvaldo D. Rivera, Michael J. Mallory, Mathieu Quesnel-Vallières, Rakesh Chatrikhi, David C. Schultz, Martin Carroll, Yoseph Barash, Sara Cherry, and Kristen W. Lynch.
Disrupting upstream translation in mRNAs is associated with human disease. David S. M. Lee, Joseph Park, Andrew Kromer, Aris Baras, Daniel J. Rader, Marylyn D. Ritchie, Louis R. Ghanem & Yoseph Barash.
Single-cell transcriptomic analysis of mIHC images via antigen mapping. Kiya W. Govek, Emma C. Troisi, Zhen Miao, Rachael G. Aubin, Steven Woodhouse, Pablo G. Camara†
FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity. Yitzhak Reizel, Ashleigh Morgan, Long Gao, Jonathan Schug, Sarmistha Mukherjee, Meilín Fernández García, Greg Donahue, Joseph A. Baur, Kenneth S. Zaret, Klaus H. Kaestner.