Counterion-mediated pattern formation in membranes containing anionic lipids

Slochower DR, Wang YH, Tourdot RW, Radhakrishnan R, Janmey PA. Counterion-mediated pattern formation in membranes containing anionic lipids. Adv Colloid Interface Sci Jan 30 2014; Summary Most lipid components of cell membranes are either neutral, like cholesterol, or zwitterionic, like phosphatidylcholine and sphingomyelin. Very few lipids, such as sphingosine, are …

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The Atherosusceptible Endothelium: Endothelial Phenotypes in Complex Haemodynamic Shear Stress Regions in vivo.

Davies PF, Civelek M, Fang Y, Fleming I. Cardiovasc Res. 2013 Jul 15 Abstract Atherosclerosis initiates at predictable focal sites and develops to a spatially regional disease with limited distribution. There is compelling evidence that links haemodynamics to the localized origin of atherosclerotic lesions. Arterial flow in vivo is unsteady, …

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Counterion-Mediated Cluster Formation by Polyphosphoinositides

Wang YH, Slochower DR, Janmey PA.. Chem Phys Lipids. 2014 Jan 15 Abstract Polyphosphoinositides (PPI) and in particular PI(4,5)P2, are among the most highly charged molecules in cell membranes, are important in many cellular signaling pathways, and are frequently targeted by peripheral polybasic proteins for anchoring through electrostatic interactions. Such …

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New Textbook: Biological Physics, by Philip Nelson

In January 2014, W.H. Freeman will publish Biological Physics: Energy, Information, Life, by Prof. Philip Nelson, with artwork by David Goodsell. Biological Physics develops classic ideas such as thermodynamic forces, transport, electrostatics, fluid motion, and continuum mechanics, all in the context of recent results in molecular motors, self-assembly, neuroscience, and …

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The Special Dean’s Awards

The Special Dean’s Awards, established during the 1989-90 academic year, honor special achievements by Penn faculty members, particularly in the development of new and innovative educational programs. The Vice Dean for Education, in consultation with the Teaching Awards Selection Committee, identifies faculty members who have made unique contributions to medical …

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