Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin. 

Deregulated Ca²⁺ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.
Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O’Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.
Sci Adv. 2017 Jun 7;3(6):e1603081. eCollection 2017 Jun. PMID: 28630914. doi: 10.1126/sciadv.1603081.