2015
Lee K, Hsiung CC, Huang P, Raj A, Blobel GA. Dynamic enhancer-gene body contacts during transcription elongation. Genes Dev. 2015 Oct 1;29(19):1992-7.
Bartman CR, Blobel GA. Perturbing Chromatin Structure to Understand Mechanisms of Gene Expression. Cold Spring Harb Symp Quant Biol. 2015 Sep 14. pii: 027359. [Epub ahead of print]
Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA.Functions of BET proteins in erythroid gene expression. Blood. 2015 Apr 30;125(18):2825-34.
Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA. Genome accessibility is widely preserved and locally modulated during mitosis. Genome Res. 2015 Feb;25(2):213-25. doi: 10.1101/gr.180646.114.
2014
Deng W, Rupon JW, Krivega I, Breda L, Motta I, Jahn KS, Reik A, Gregory PD, Rivella S, Dean A, Blobel GA. Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell. 2014 Aug 14;158(4):849-60.
Deng W, Blobel GA. Manipulating nuclear architecture. Curr Opin Genet Dev. 2014 Apr;25:1-7.
Campbell AE, Hsiung CC, Blobel GA.Comparative analysis of mitosis-specific antibodies for bulk purification of mitotic populations by fluorescence-activated cell sorting. Biotechniques. 2014 Feb 1;56(2):90-1, 93-4.
Zheng R, Rebolledo-Jaramillo B, Zong Y, Wang L, Russo P, Hancock W, Stanger BZ, Hardison RC, Blobel GA. Function of GATA factors in the adult mouse liver. PLoS One. 2013 Dec 18;8(12):e83723.
2013
Hardison RC, Blobel GA. Genetics. GWAS to therapy by genome edits? Science. 2013 Oct 11;342(6155):206-7.
Blobel GA, Hardison RC. A cluster to remember. Cell. 2013 Aug 15;154(4):718-20.
Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA. Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood. 2013 Jun 27;121(26):5218-27.
Kadauke S, Blobel GA. Mitotic bookmarking by transcription factors. Epigenetics Chromatin. 2013 Apr 2;6(1):6.
2012
Kadauke S, Blobel GA. “Remembering” tissue-specific transcription patterns through mitosis. Cell Cycle. 2012 Nov 1;11(21):3911-2.
Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA. Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell. 2012 Aug 17;150(4):725-37.
Deng W, Lee J, Wang H, Miller J, Reik A, Gregory PD, Dean A, Blobel GA.Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell. 2012 Jun 8;149(6):1233-44.
2011
Short hairpin RNA screen reveals bromodomain proteins as novel targets in acute myeloid leukemia.
Blobel GA, Kalota A, Sanchez PV, Carroll M. Cancer Cell. 2011 Sep 13;20(3):287-8.
Lamonica JM, Deng W, Kadauke S, Campbell AE, Gamsjaeger R, Wang H, Cheng Y, Billin AN, Hardison RC, Mackay JP, Blobel GA. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proc Natl Acad Sci. 2011 May 31;108(22):E159-68.
2010
Zheng R, Blobel GA. GATA Transcription Factors and Cancer. Genes Cancer. 2010 Dec;1(12):1178-88.
Deng W, Blobel GA. Do chromatin loops provide epigenetic gene expression states? Curr Opin Genet Dev. 2010 Oct;20(5):548-54.
Miccio A, Blobel GA. Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes. Mol Cell Biol. 2010 Jul;30(14):3460-70.
Gregory GD, Miccio A, Bersenev A, Wang Y, Hong W, Zhang Z, Poncz M, Tong W, Blobel GA. FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood. 2010 Mar 18;115(11):2156-66.
Miccio A, Wang Y, Hong W, Gregory GD, Wang H, Yu X, Choi JK, Shelat S, Tong W, Poncz M, Blobel GA. NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. EMBO J. 2010 Jan 20;29(2):442-56.
2009
Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR. A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Mol Cell. 2009 Dec 25;36(6):970-83.
Tripic T, Deng W, Cheng Y, Zhang Y, Vakoc CR, Gregory GD, Hardison RC, Blobel GA. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood. 2009 Mar 5;113(10):2191-201.
2008
Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
Mol Cell Biol. 2008 Apr;28(8):2825-39.
Jing H, Vakoc CR, Ying L, Mandat S, Wang H, Zheng X, Blobel GA. Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Mol Cell. 2008 Feb 1;29(2):232-42.
2002-2007
Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani E, Blobel GA. Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes. Mol Cell Biol. 2007 Dec;27(24):8466-79.
Vakoc CR, Sachdeva MM, Wang H, Blobel GA.Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol. 2006 Dec;26(24):9185-95.
Lamonica JM, Vakoc CR, Blobel GA. Acetylation of GATA-1 is required for chromatin occupancy. Blood. 2006 Dec 1;108(12):3736-8.
Vakoc CR, Mandat SA, Olenchock BA, Blobel GA. Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell. 2005 Aug 5;19(3):381-91.
Hong W, Nakazawa M, Chen YY, Kori R, Vakoc CR, Rakowski C, Blobel GA. FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J. 2005 Jul 6;24(13):2367-78. Epub 2005 May 26.
Vakoc CR, Letting DL, Gheldof N, Sawado T, Bender MA, Groudine M, Weiss MJ, Dekker J, Blobel GA. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol Cell. 2005 Feb 4;17(3):453-62.
Letting DL, Chen YY, Rakowski C, Reedy S, Blobel GA. Context-dependent regulation of GATA-1 by friend of GATA-1. Proc Natl Acad Sci. 2004 Jan 13;101(2):476-81.
Letting DL, Rakowski C, Weiss MJ, Blobel GA. Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Mol Cell Biol. 2003 Feb;23(4):1334-40.
Hong W, Resnick RJ, Rakowski C, Shalloway D, Taylor SJ, Blobel GA. Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68. Mol Cancer Res. 2002 Nov;1(1):48-55.
Wang X, Crispino JD, Letting DL, Nakazawa M, Poncz M, Blobel GA. Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. EMBO J. 2002 Oct 1;21(19):5225-34.
Hong W, Kim AY, Ky S, Rakowski C, Seo SB, Chakravarti D, Atchison M, Blobel GA. Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1. Mol Cell Biol. 2002 Jun;22(11):3729-43.
Blobel GA. CBP and p300: versatile coregulators with important roles in hematopoietic gene expression. J Leukoc Biol. 2002 Apr;71(4):545-56. Review.