Our Leducq Cytoskeletal Network has begun!

Our Leducq Cytoskeletal Network has begun!

On January 1st 2021 we officially kicked off the Leducq Cytoskeletal Network (LCN).  This Trans-Atlantic Network of Excellence brings together 7 different labs from the U.S. and Europe all working to better understanding how the cytoskeleton contributes to normal and pathological functions of heart muscle cells,

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Collaboration with Ionis Pharmaceuticals on new therapies for neurodevelopment disorders

Collaboration with Ionis Pharmaceuticals on new therapies for neurodevelopment disorders

We’re thrilled to have entered into a sponsored research agreement with Ionis Pharmaceuticals, the leading experts on antisense technology.  The partnership will be between Ionis and the Prosser and Davidson labs at Penn and CHOP, respectively, and is focused on testing a new approach to treat STXBP1 disorders using antisense oligonucleotides.

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Congrats Julie on your cover story in Circ Res!

Congrats Julie on your cover story in Circ Res!

Julie Heffler’s work on how a balance of cytoskeletal forces maintains nuclear integrity in the cardiomyocyte earned cover honors for the Jan 2020 issue of Circulation Research.  Congrats Julie, well deserved!

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Matt’s work on microtubules in diastolic dysfunction published in Circulation!

Matt’s work on microtubules in diastolic dysfunction published in Circulation!

Congrats Matt – this work involved many overnight sessions conducting mechanical measurements on myocardial tissue preparations from transplant patients – when the heart often comes in around 2AM! But after all if it’s not hard, it’s probably not worth doing 🙂

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Press for Chen et al., Nature Med 2018

Press for Chen et al., Nature Med 2018

An excellent, concise highlight in Nature Reviews Cardiology:

https://rdcu.be/18Sv

A longer piece by Medical News Today:

https://www.medicalnewstoday.com/articles/322192.php

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Prosser lab work published in Nature Medicine!

Prosser lab work published in Nature Medicine!

Christina’s paper on microtubules in human heart failure was published online in Nature Medicine.  We found that suppressing stable microtubules can boost contractile function of heart cells from patients with heart failure – check it out: https://www.nature.com/articles/s41591-018-0046-2

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Ben wins AHA Outstanding Early Career Investigator Award

Ben was honored with the Outstanding Early Career Investigator Award from the American Heart Association.  Read all about it here:  https://www.pennmedicine.org/news/news-releases/2017/july/cardiology-researcher-wins-aha-outstanding-early-career-investigator-award

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Welcome Alex S!

Welcome Alex S., aka Xander/Ax, to the Prosser lab!  Read more about Alex and our other lab members under the “People” tab.

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Congrats Matt and Pat!

Big congrats to Matt C. and Pat R., who were awarded post-doctoral fellowships from the American Heart Association and National Institutes of Health!

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Tugging on the heart strings this Valentine’s day

Who knew microtubules could be romantic?  The HHMI celebrates cool science and heart puns.  http://www.hhmi.org/biointeractive/tugging-cellular-heartstrings

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Biophysics in NOLA

Join us at Biophysics in New Orleans, where Matt Caporizzo, Christina Chen, Julie Heffler, and Pat Robison will all be presenting their work.  And eating beignets!

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Conferences Galore

The Prosser lab has a busy June discussing their work. Ben was lucky enough to present the lab’s work to two very different but fantastic audiences at the EMBO Microtubule Symposium in Heidelberg and at the Cardiac Gordon Research Conference in New Hampshire.

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NIH Director blog on microtubule buckling in the heart

Our work was selected by NIH Director Francis Collins for his blog! Check out the story here, and look under the research tab for more in the popular press.
https://directorsblog.nih.gov/2016/05/03/a-look-inside-a-beating-heart-cell/

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Prosser Lab study published in Science!

Our labs study on microtubule buckling in the heart was published in this weeks edition of Science. Congrats to Pat and all other authors involved. Read the study here: http://science.sciencemag.org/content/352/6284/aaf0659

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Media Coverage of Robison et al., Science 2016

STATnews interviewed Dr. Prosser regarding our recent study on microtubule buckling in the heart. Check out the story here: http://us11.campaign-archive2.com/?u=f8609630ae206654824f897b6&id=beb156bae0

Science Daily also covered the story. Read about it here! https://www.sciencedaily.com/releases/2016/04/160421145756.htm

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