Select Publications

Transient, ligand-dependent arrest of the androgen receptor in sub-nuclear foci alters phosphorylation and co-activator interactions.

Black, B.E., M.J. Vitto, D. Gioeli, A. Spencer, N. Afshar, M.R. Conaway, M.J. Weber, and B.M. Paschal. 2004. Transient, ligand-dependent arrest of the androgen receptor in sub-nuclear foci alters phosphorylation and co-activator interactions. Mol. Endocrinol. 18:834-850. (contributed equally) PMID: 14684849

Paschal. 2002. Ca2+-dependent nuclear export mediated by calreticulin.

Holaska, J.M., B.E. Black, F. Rastinejad, and B.M. Paschal. 2002. Ca2+-dependent nuclear export mediated by calreticulin. Mol. Cell. Biol. 22:6286-6297. PMID: 12167720

DNA binding domains in diverse nuclear receptors function as nuclear export signals.

Black, B.E., J.M. Holaska, F. Rastinejad, and B.M. Paschal. 2001. DNA binding domains in diverse nuclear receptors function as nuclear export signals. Curr. Biol. 11:1749-1758. PMID: 11719216

RNA export mediated by Tap involves NXT1-dependent interactions with the nuclear pore complex.

Lévesque, L., B.W. Guzik, T. Guan, J. Coyle, B.E. Black, D. Rekosh, M.-L. Hammarskjöld, and B.M. Paschal. 2001. RNA export mediated by Tap involves NXT1-dependent interactions with the nuclear pore complex. J. Biol. Chem. 276:44953-44962. PMID: 11579093

NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.

Guzik, B.W., L. Lévesque, S. Prasad, Y.C. Bor, B.E. Black, B.M. Paschal, D. Rekosh, and M.L. Hammarskjöld. 2001. NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells. Mol. Cell. Biol. 21:2545-2554. PMID: 11259602

NXT1 is necessary for the terminal step of Crm1-mediated nuclear export.

Black, B.E., J.M. Holaska, L. Lévesque, B. Ossareh-Nazari, C. Gwizdek, C. Dargemont, and B.M. Paschal. 2001. NXT1 is necessary for the terminal step of Crm1-mediated nuclear export. J. Cell Biol. 152:141-155. PMID: 11149927

Calreticulin is a receptor for nuclear export.

Holaska, J.M., B.E. Black, D.C. Love, J.A. Hanover, J. Leszyk, and B.M. Paschal. 2001. Calreticulin is a receptor for nuclear export. J. Cell Biol. 152:127-140. PMID: 11149926

RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA In vitro.

Ossareh-Nazari, B., C. Maison, B.E. Black, L. Lévesque, B.M. Paschal, and C. Dargemont. 2000. RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA In vitro. Mol. Cell. Biol. 20:4562-4671. PMID: 10848583

Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran.

Steggerda, S.M., B.E. Black, and B.M. Paschal. 2000. Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran. Mol. Biol. Cell. 11:703-719. PMID: 10679025

Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export.

Black, B.E., L. Lévesque, J.M. Holaska, T.C. Wood, and B.M. Paschal. 1999. Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export. Mol. Cell. Biol. 19:8616-8624. PMID: 10567585