Publications - Dr. Ben Black's Laboratory

HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications

Langelier, M.F., R. Billur, A. Sverzhinsky, B.E. Black, and J.M. Pascal. 2021. HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications. Nat. Commun. 12:6675. [PMID: 34795260]

Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub

Salinas-Luypaert, C.^†, P.K. Allu^†, G.A. Logsdon, J.M. Dawicki-McKenna, C.W. Gambogi, D. Fachinetti*, and B.E. Black*. 2021. Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A^K124ub. Cell Rep. 37:109924. (*corresponding authors; ^†contributed equally). [PMID: 34731637]

Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts

Tarasovetc, E.V., P.K. Allu, R.T. Wimbish, J.G. DeLuca, I.M. Cheeseman, B.E. Black*, and E.L. Grishchuk*. 2021. Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts. Mol. Biol. Cell, 32:1241-1255. (*corresponding authors). [PMID: 33956511]

Rapid detection and signaling of DNA damage by PARP-1

Pandey, N., and B.E. Black*. 2021. Rapid detection and signaling of DNA damage by PARP-1. Trends Biochem. Sci.,46:744-757. (*corresponding author). [PMID: 33674152]

Maternal inheritance of centromeres through the germline

Das, A., B.E. Black*, and M.A. Lampson*. 2020. Maternal inheritance of centromeres through the germline. Curr. Top. Dev. Biol., 140:35-54 (* corresponding authors). [PMID:32591081]

Centromere identity and function put to use: construction and transfer of mammalian artificial chromosomes to animal models

Yang, Y., M.A. Lampson*, and B.E. Black*. 2020. Centromere identity and function put to use: construction and transfer of mammalian artificial chromosomes to animal models.Essays Biochem., 64:185-192. (*corresponding authors). [PMID: 32501473]

The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle

Kixmoeller, K., P.K. Allu, and B.E. Black*. 2020. The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle. Open Biol., 10:200051. (*corresponding author). [PMID: 32516549]

The unique kind of human artificial chromosome: bypassing the requirement for repetitive centromere DNA

Gambogi, C.W., J.M. Dawicki-McKenna, G.A. Logsdon, and B.E. Black*. 2020. The unique kind of human artificial chromosome: bypassing the requirement for repetitive centromere DNA. Exp. Cell Res. 391:111978. (*corresponding author) [PMID: 32246994]

Structural basis for allosteric PARP-1 retention on DNA breaks

Zandarashvili, L.^†, M.F. Langelier^†, U.K. Velagapudi, M.A. Hancock, J.D. Steffen, R. Billur, Z.M. Hannan, A.J. Wicks, D.B. Krastev, S.J. Pettitt, C.J. Lord, T.T. Talele, J.M. Pascal*, and B.E. Black*. 2020. Structural basis for allosteric PARP-1 retention on DNA breaks. Science, 368:eaax6367. (*corresponding authors; ^†contributed equally). [PMID: 32241924]

Structure of the human core centromeric nucleosome complex

Allu, P.K., J.M. Dawicki-McKenna, T. Van Eeuwen, M. Slavin, M. Braitbard, C. Xu, N. Kalisman, K. Murakami, and B.E. Black*. 2019. Structure of the human core centromeric nucleosome complex. Curr. Biol., 29:2625-2639. (*corresponding author). [PMID: 31353180]

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