Select Publications

Ultrastructure of human brain tissue vitrified directly from autopsy revealed by cryo-ET with cryo-plasma FIB milling

Creekmore, B.C., K. Kixmoeller, B.E. Black, E.B. Lee, and Y.-W. Chang. 2024. Ultrastructure of human brain tissue vitrified directly from autopsy revealed by cryo-ET with cryo-plasma FIB milling. Nat. Commun. 15:2660. (contributed equally) [PMID: 38531877]

Efficient formation of single-copy human artificial chromosomes

Gambogi, C.W., G.J. Birchak, E. Mer, D.M. Brown, G. Yankson, K. Kixmoeller, J.N. Gavade, J.L. Espinoza, P. Kashyap, G.A. Logsdon, P. Heun, J.I. Glass, and B.E. Black*. 2024. Efficient formation of single-copy human artificial chromosomes. Science, 383:1344-1349. (*corresponding author) [PMID: 38513017]

Structural basis for the phase separation of the chromosome passenger complex

Bryan, N.W., A. Ali, E. Niedzialkowska,, L. Mayne, P.T. Stukenberg, and B.E. Black*. 2024. Structural basis for the phase separation of the chromosome passenger complex. eLife, 13:e92079. (*corresponding author) [PMID: 38456462]

Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks

Velagapudi, U.K., É. Rouleau-Turcotte, R. Billur, X. Shao, M. Patil, B.E. Black*, J.M. Pascal*, and T. Talele*. 2024. Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks. Biochem. J., 481:437-460. (*corresponding authors, contributed equally) [PMID: 38372302]

Centromere innovations within a mouse species

Gambogi, C.W., N. Pandey, J.M. Dawicki-McKenna, U.P. Arora, M.A. Liskovykh, J. Ma, P. Lamelza, V. Larionov, M.A. Lampson, G.A. Logsdon, B.L. Dumont, and B.E. Black*. 2023. Centromere innovations within a mouse species. Sci. Adv., 9:eadi5764. (*corresponding author; contributed equally) [PMID: 37967185]

Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly

Das, A., K.G. Boese, K. Tachibana, S.H. Baek, M.A. Lampson*, and B.E. Black*. 2023. Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly. Curr. Biol., 33:3759-3765. (*corresponding authors) [PMID:37582374]

The structural basis of the multi-step allosteric activation of Aurora B kinase

Segura-Peña, D., O. Hovet, H. Gogoi, J.M. Dawicki-McKenna, S.M.H. Wøien, M. Carrer, B.E. Black, M. Cascella, and N. Sekulic. 2023. The structural basis of the multi-step allosteric activation of Aurora B kinase. eLife, 12:e85328[PMID: 36001657]

In situ structure determination of bacterial surface nanomachines using cryo-electron tomography

Lai, L., Y.-W. Cheung, M. Martinez, K. Kixmoeller, L. Palao III, S. Steimle, M.-C. Ho, B.E. Black, E.-M. Lai, and Y.-W. Chang. 2023. In situ structure determination of bacterial surface nanomachines using cryo-electron tomography. Methods Mol. Biol., 2646:211-248. [PMID:36842118]

Molecular basis of UHRF1 allosteric activation for synergistic histone modification binding by PI5P

Mandal, P., K. Eswara, Z. Yerkesh, V. Kharchenko, L. Zandarashvili, K. Szczepski, D. Bensaddek, L. Jaremko, B.E. Black, and W. Fischle. 2022. Molecular basis of UHRF1 allosteric activation for synergistic histone modification binding by PI5P. Sci. Adv., 8:eabl9461[PMID: 36001657]

Chromosomes: a nuclear neighborhood conducive to centromere formation

Gavade, J.N., and B.E. Black*. 2022. Chromosomes: a nuclear neighborhood conducive to centromere formation. Curr. Biol., 32:R776-R778. (*corresponding author). [PMID:35882197]