His research aims to understand the structure and function of the brain. To do so, his lab takes a comparative approach and engineers molecular, viral, and sequencing technologies to measure neuronal connectivity networks and gene expression at scale in disease models and a wide range of vertebrates. He developed the first barcode sequencing-based approaches to map neuronal connectivity, increasing throughput of single-neuron mapping by orders of magnitude and opening the door to single-cell comparative connectomics. His lab complements these barcoding approaches by in situ sequencing of barcodes and genes. Leveraging these technologies, they ask questions including: How do new brain regions and connections evolve to support new computations? What are the organizing principles and fundamental circuit motifs of the vertebrate brain? And how do drugs of abuse and neurodevelopmental disorders break these principles? His work is highly interdisciplinary, residing at the interface of molecular engineering, neuroscience, synthetic and evolutionary biology, genomics, virology, and computational biology.
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Justus Kebschull, Ph.D. (Johns Hopkins) – Hybrid Epigenetics Monthly Seminar Series
January 11 @ 4:00 pm - 5:00 pm
Justus Kebschull, Ph.D.
Assistant Professor, Biomedical Engineering
Johns Hopkins University
The Kebschull Lab
Dr. Kebschull grew up in Germany and received his BA and MSci from the University of Cambridge, UK in 2011. He pursued his PhD in Tony Zador’s lab at CSHL where he developed DNA sequencing-based tools for brain mapping. In 2017 he joined Liqun Luo’s lab at Stanford University as a postdoctoral fellow, working on the evolution of the cerebellar nuclei, before coming to JHU in 2021.
Hosted by Liz Heller, Ph.D.