Assistant Professor of Bioengineering
New York Stem Cell Foundation – Robertson Investigator

Lab Website

Faculty Website

Contact Information

Department of Bioengineering
School of Engineering and Applied Sciences
University of Pennsylvania
210 South 33rd Street
Lab Location: 240 Skirkanich Hall
Office Location: 304 Hayden Hall
Philadelphia, PA 19104
Office: (215) 898-4121

Publication Links

Research Interest

Epigenomics and Systems Neurobiology Lab: The Cremins Lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of neural cell function. We employ systems level experimental and computational approaches to (1) create high-resolution 3-D genome architecture maps and (2) integrate 3-D architecture maps with genome-wide maps of epigenetic modifications and gene expression. Current work is focused on understanding the role for higher-order chromatin organization during differentiation of embryonic stem cells into neurons, during reprogramming of neurons into induced pluripotent stem cells and in models of neurodegenerative disease.