February 7, 2019

Rubenstein Auditorium and Lobby

Smilow Center for Translational Research
Perelman School of Medicine, University of Pennsylvania

2019 Awakening and Calming The Epigenome Symposium


James (Jay) Bradner, M.D.

President of the Novartis Institutes for BioMedical Research (NIBR)


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Rudolf Jaenisch, Ph.D.

Professor of Biology; Founding Member, Whitehead Institute; Member, Institute of Medicine


Rudolf Jaenisch is a Founding Member of the Whitehead Institute for Biomedical Research and a Professor of Biology at the Massachusetts Institute of Technology. He is a pioneer in making transgenic mice, some of which have produced important advances in understanding cancer, neurological and connective tissue diseases, and developmental abnormalities and has explored basic questions such as the role of DNA modification, genomic imprinting and X chromosome inactivation. The laboratory is renowned for its expertise in cloning mice and in studying the myriad factors that contribute to the success and failure cellular reprogramming. More recently the lab has focused on using the iPS cell system to study diseases such as Alzheimer’s, Parkinson’s and Autism.
Dr. Jaenisch is a Member of the National Academy of Sciences and the International Society for Stem Cell Research. In 1996 he was honored with the Boehringer Mannheim Molecular Bioanalytics Prize, in 2001 was the recipient of the first ever Peter Gruber Foundation Award in Genetics, in 2002 won the Robert Koch Prize for Excellence in Scientific Achievement, the March of Dimes Prize in 2015 and in 2011 was a recipient of the United States National Medal of Science. In 2014 he was president of the ISSCR.


Schedule subject to change. Final schedule will be available week before symposium.
(Click the arrow to display the schedule)

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Rubenstein Auditorium and Lobby

Smilow Center for Translational Research
Perelman School of Medicine, University of Pennsylvania
3400 Civic Center Blvd
Philadelphia, PA 19104



8:30 a.m.


9:00 a.m.

Welcome and Introductions

J Larry Jameson, M.D., Ph.D.
Robert G. Dunlop Professor of Medicine
Executive Vice President, University of Pennsylvania Health System
Dean, Perelman School of Medicine at the University of Pennsylvania
Shelley L. Berger, Ph.D.
Daniel S. Och University Professor
PIK Professor, Depts., of Cell and Developmental Biology; Biology; Genetics Director, Epigenetics Institute, Perelman School of Medicine

Session 1

Chair: TBD

9:10 a.m.


James (Jay) Bradner, M.D., President of the Novartis Institutes for Biomedical Research (NIBR)

10:00 a.m.


Junwei Shi Ph.D., Assistant Professor of Cancer Biology, PSOM

10:30 a.m.

Coffee Break & Poster Session

10:50 a.m.

CRISPR-Based Epigenome Editing for Gene Therapy, Cell Programming, and Functional Epigenomic

Charles A. Gersbach, Ph.D., Rooney Family Associate Professor of Biomedical Engineering at Duke University

11:30 a.m.

Metabolic signaling to the epigenome

Kathryn E. Wellen, Ph.D., Associate Professor of Cancer Biology, PSOM

12:00 p.m.

Speed Talks


12:30 p.m.

Lunch and Poster Session

Session 2

Chair: TBD

2:00 p.m.


Ming-Ming Zhou, Ph.D., Professor and Chair of Pharmacological Sciences; Co-Director of the Experimental Therapeutics Institute; Professor of Oncological Science at the Icahn School of Medicine at Mount Sinai

2:40 p.m.

The Chromatin Landscape in Neuronal Function and Dysfunction

Erica Korb, Ph.D., Assistant Professor of Genetics, PSOM

3:10 p.m.

Coffee Break

3:30 p.m.


Yael David, Ph.D., Assistant Professor at Memorial Sloan Kettering Cancer Center

4:10 p.m.


Montserrat C. Anguera, Ph.D., B.A, Assistant Professor of the Department of Biomedical Sciences at Penn Vet

4:40 p.m.


Craig B. Thompson, M.D., President and CEO of Memorial Sloan Kettering Cancer Center

5:20 p.m.

Stem cells and epigenetic regulation in development and disease

Rudolf Jaenisch, M.D., Professor of Biology at the Massachusetts Institute of Technology; Founding Member of the Whitehead Institute for Biomedical Research

6:10 p.m.

Closing Remarks and Poster Prize Winners Announcement

6:15 p.m.



Yael David, Ph.D.

Assistant Member
Chemical Biology Program
Memorial Sloan Kettering Cancer Center
Lab Website

Montserrat C. Anguera, Ph.D., B.A.

Assistant Professor, Department of Biomedical Sciences
University of Pennsylvania School of Veterinary Medicine
Lab Website



Registration and abstract submission closes on January 4, 2018.

**The top 6 abstracts will be selected for 5-minute speed talks at the symposium.

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