February 7, 2019
Rubenstein Auditorium and Lobby
Smilow Center for Translational Research
Perelman School of Medicine, University of Pennsylvania
2019 Awakening and Calming The Epigenome Symposium
KEYNOTE SPEAKERS
Rudolf Jaenisch, Ph.D.
Professor of Biology; Founding Member, Whitehead Institute; Member, Institute of Medicine
MIT
https://biology.mit.edu/profile/rudolf-jaenisch/
Rudolf Jaenisch is a Founding Member of the Whitehead Institute for Biomedical Research and a Professor of Biology at the Massachusetts Institute of Technology. He is a pioneer in making transgenic mice, some of which have produced important advances in understanding cancer, neurological and connective tissue diseases, and developmental abnormalities and has explored basic questions such as the role of DNA modification, genomic imprinting and X chromosome inactivation. The laboratory is renowned for its expertise in cloning mice and in studying the myriad factors that contribute to the success and failure cellular reprogramming. More recently the lab has focused on using the iPS cell system to study diseases such as Alzheimer’s, Parkinson’s and Autism.
Dr. Jaenisch is a Member of the National Academy of Sciences and the International Society for Stem Cell Research. In 1996 he was honored with the Boehringer Mannheim Molecular Bioanalytics Prize, in 2001 was the recipient of the first ever Peter Gruber Foundation Award in Genetics, in 2002 won the Robert Koch Prize for Excellence in Scientific Achievement, the March of Dimes Prize in 2015 and in 2011 was a recipient of the United States National Medal of Science. In 2014 he was president of the ISSCR.
SCHEDULE
Schedule subject to change. Final schedule will be available week before symposium.
(Click the arrow to display the schedule)
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Rubenstein Auditorium and Lobby
Smilow Center for Translational Research
Perelman School of Medicine, University of Pennsylvania
3400 Civic Center Blvd
Philadelphia, PA 19104
Info
Breakfast
Welcome and Introductions
Jonathan A. Epstein, M.D.
William Wikoff Smith Professor of Cardiovascular Research
Executive Vice Dean and Chief Scientific Officer, Perelman School of Medicine
Shelley L. Berger, Ph.D.
Daniel S. Och University Professor
PIK Professor, Depts., of Cell and Developmental Biology; Biology; Genetics Director, Epigenetics Institute, Perelman School of Medicine
Chair: Jennifer E. Phillips-Cremins, Ph.D.
Assistant Professor of Bioengineering, Penn
CRISPR-Based Epigenome Editing for Gene Therapy, Cell Programming, and Functional Epigenomic
Charles A. Gersbach, Ph.D., Rooney Family Associate Professor of Biomedical Engineering at Duke University
9:45 a.m.
Identifying transcriptional vulnerability in acute myeloid leukemia
JunweiShi Ph.D., Assistant Professor of Cancer Biology, PSOM
Coffee Break
Metabolic signaling to the epigenome
Kathryn E. Wellen, Ph.D., Associate Professor of Cancer Biology, PSOM
Stem cells and epigenetic regulation in development and disease
Rudolf Jaenisch, M.D., Professor of Biology at the Massachusetts Institute of Technology; Whitehead Institute for Biomedical Research
Metabolic signaling to the epigenome
Kathryn E. Wellen, Ph.D., Associate Professor of Cancer Biology, Perelman School of Medicine
Chair: Marisa Bartolomei, Ph.D.
Perelman Professor of Cell and Developmental Biology; Co-Director, Epigenetics Institute
Speed Talks
1.Robert Warneford-Thomas (Bonasio Lab)
2.Dongyin Guan (Lazar Lab)
3.Aidan Hancock (Epstein Lab)
4.Reyaz Rasool (Asangani Lab)
5.Meilin Fernandez-Garcia (Zaret Lab)
6.Tzachi Reizel (Kaestner Lab)
Lunch and Poster Session
Chair: Roberto Bonasio, Ph.D.
Assistant Professor of Cell and Developmental Biology, Perelman School of Medicine
From Epigenetic Mechanism to New Targeted Therapy
Ming-Ming Zhou, Ph.D., Dr. Harold and Golden Lamport Professorship in Physiology and Biophysics; Professor and Chairman, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
The Chromatin Landscape in Neuronal Function and Dysfunction
Erica Korb, Ph.D., Assistant Professor of Genetics, Perelman School of Medicine
Capturing TET-mediated DNA demethylation in action
Rahul M. Kohli, M.D., Ph.D., Assistant Professor of Medicine and Biochemistry and Biophysics, Perelman School of Medicine
Coffee Break
Dynamic mechanisms of XCI maintenance in female lymphocytes & female-biased autoimmunity
Montserrat C. Anguera, Ph.D., B.A, Assistant Professor of the Department of Biomedical Sciences at Penn Vet
Reversible histone glycation drives disease-associated changes in chromatin architecture
Yael David, Ph.D., Assistant Professor at Memorial Sloan Kettering Cancer Center
Closing Remarks and Poster Prize Winners Announcement
by Gerd Blobel, M.D., Ph.D., Frank E. Weise III Professor of Pediatrics; Co-Director, Epigenetics Institute
Reception
ADDITIONAL SPEAKERS
Montserrat C. Anguera, Ph.D., B.A.
Assistant Professor, Department of Biomedical Sciences
University of Pennsylvania School of Veterinary Medicine
Lab Website
Yael David, Ph.D.
Assistant Member
Chemical Biology Program
Memorial Sloan Kettering Cancer Center
Lab Website
SYMPOSIUM FLYER
REGISTER
Registration and abstract submission closes on January 4, 2018.
**The top 6 abstracts will be selected for 5-minute speed talks at the symposium.