Ken Zaret was elected as a 2021 fellow of the American Academy of Arts & Sciences. Congratulations Ken!
Ken Zaret is featured in the newly posted episode “Pioneer Transcription Factors and Their Influence on Chromatin Structure”
Shelley Berger is featured in an episode from last year, “Epigenetic Mechanisms of Aging and Longevity”
You can find both podcasts here (Episodes 15 and 34): https://www.activemotif.com/podcasts
New genomic analyses indicate that pioneer transcription factors can sample a diverse repertoire of common binding sites among different cell types and become enriched where they cooperate with other factors specific to each cell. Pioneer-factor binding is mechanistically separate from, and is necessary for, subsequent phenomena of chromatin opening and epigenetic memory in vivo.